ISHIMARU YOSHIRO
   Department   Undergraduate School  , School of Agriculture
   Position   Professor
Research Period 2010~2012
Research Topic Visualization of the neural circuit transmitting taste information and elucidation of mechanisms underlying its development and maintenance
Research Type KAKENHI Research
Consignor Japan Society for the Promotion of Science
Research Program Type Grant-in-Aid for Young Scientists (A)
KAKENHI Grant No. 22688010
Responsibility Representative Researcher
Representative Person ISHIMARU Yoshiro
Details To elucidate the mechanism underlying the transmission of taste information from taste buds to the brain, the neural circuit transmitting sour taste information was first visualized by generating transgenic mice in which a transneuronal tracer, wheat germ agglutinin, was specifically expressed in sour-sensing cells. It has been suggested that the neural circuits transmitting pleasant (sweet and umami) and aversive (bitter and sour) tastes were mutually segregated in the cranial sensory ganglia.