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SHIMADA TOMOHIRO
Department Undergraduate School , School of Agriculture Position Associate Professor |
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| Language | English |
| Publication Date | 2011 |
| Type | Academic Journal |
| Peer Review | Peer reviewed |
| Title | Novel roles of cAMP receptor protein (CRP) in regulation of transport and metabolism of carbon sources. |
| Contribution Type | Co-authored (first author) |
| Journal | PloS one |
| Journal Type | Another Country |
| Volume, Issue, Page | 6(6),pp.e20081 |
| Authorship | Lead author |
| Author and coauthor | Shimada Tomohiro, Fujita Nobuyuki, Yamamoto Kaneyoshi, Ishihama Akira |
| Details | CRP (cAMP receptor protein), the global regulator of genes for carbon source utilization in the absence of glucose, is the best-studied prokaryotic transcription factor. A total of 195 target promoters on the Escherichia coli genome have been proposed to be under the control of cAMP-bound CRP. Using the newly developed Genomic SELEX screening system of transcription factor-binding sequences, however, we have identified a total of at least 254 CRP-binding sites. Based on their location on the E. coli genome, we ... |
| DOI | 10.1371/journal.pone.0020081 |
| ISSN | 1932-6203 |
| PMID | 21673794 |