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SHIMADA TOMOHIRO
Department Undergraduate School , School of Agriculture Position Associate Professor |
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| Language | English |
| Publication Date | 2013/02 |
| Type | Academic Journal |
| Peer Review | Peer reviewed |
| Title | Novel regulator PgrR for switch control of peptidoglycan recycling in Escherichia coli. |
| Contribution Type | Co-authored (first author) |
| Journal | Genes to cells : devoted to molecular & cellular mechanisms |
| Journal Type | Another Country |
| Volume, Issue, Page | 18(2),pp.123-34 |
| Authorship | Lead author |
| Author and coauthor | Shimada Tomohiro, Yamazaki Kaoru, Ishihama Akira |
| Details | Peptidoglycan (PG), also designated as murein, forms a skeletal mesh within the periplasm of bacterial membrane. PG is a metabolically stable cell architecture in Escherichia coli, but under as yet ill-defined conditions, a portion of PG is degraded, of which both amino sugar and peptide moieties are either recycled or used as self-generated nutrients for cell growth. At present, the control of PG degradation remains uncharacterized. Using the Genomic SELEX screening system, we identified an uncharacterized transcription factor YcjZ is a repressor of the expression of the initial step enzymes for PG peptide degradation. ... |
| DOI | 10.1111/gtc.12026 |
| ISSN | 1365-2443 |
| PMID | 23301696 |