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SHIMADA TOMOHIRO
Department Undergraduate School , School of Agriculture Position Associate Professor |
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| Language | English |
| Publication Date | 2015/11 |
| Type | Academic Journal |
| Peer Review | Peer reviewed |
| Title | Expanded roles of two-component response regulator OmpR in Escherichia coli: genomic SELEX search for novel regulation targets. |
| Contribution Type | Co-authored (first author) |
| Journal | Genes to cells : devoted to molecular & cellular mechanisms |
| Journal Type | Another Country |
| Volume, Issue, Page | 20(11),pp.915-31 |
| Authorship | Lead author |
| Author and coauthor | Shimada Tomohiro, Takada Hiraku, Yamamoto Kaneyoshi, Ishihama Akira |
| Details | The two-component system (TCS) is a sophisticated bacterial signal transduction system for regulation of genome transcription in response to environmental conditions. The EnvZ-OmpR system is one of the well-characterized TCS of Escherichia coli, responding to changes in environmental osmolality. Regulation has largely focused on the differential expression of two porins, OmpF and OmpC, which transport small molecules across the outer membrane. Recently, it has become apparent that OmpR serves a more global regulatory role and regulates additional targets. To identify the entire set of regulatory targets of OmpR, we performed ... |
| DOI | 10.1111/gtc.12282 |
| ISSN | 1365-2443 |
| PMID | 26332955 |