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SHIMADA TOMOHIRO
Department Undergraduate School , School of Agriculture Position Associate Professor |
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| Language | English |
| Publication Date | 2017/07 |
| Type | Academic Journal |
| Peer Review | Peer reviewed |
| Title | A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation. |
| Contribution Type | Co-authored (other than first author) |
| Journal | FEBS letters |
| Journal Type | Another Country |
| Volume, Issue, Page | 591(13),pp.2019-2031 |
| Author and coauthor | Sugino Hirotaka, Usui Takanori, Shimada Tomohiro, Nakano Masahiro, Ogasawara Hiroshi, Ishihama Akira, Hirata Akira |
| Details | RcdA is a regulator of curlin subunit gene D, the master regulator of biofilm formation in Escherichia coli. Here, we determined the X-ray structure of RcdA at 2.55 Å resolution. RcdA consists of an N-terminal DNA-binding domain (DBD) containing a helix-turn-helix (HTH) motif and a C-terminal dimerization domain, and forms a homodimer in crystals. A computational docking model of the RcdA-DNA complex allowed prediction of the candidate residues responsible for DNA binding. ... |
| DOI | 10.1002/1873-3468.12713 |
| ISSN | 1873-3468 |
| PMID | 28608551 |