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SHIMADA TOMOHIRO
Department Undergraduate School , School of Agriculture Position Associate Professor |
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| Language | English |
| Publication Date | 2018/01 |
| Type | Academic Journal |
| Peer Review | Peer reviewed |
| Title | Identification of YbhA as the pyridoxal 5'-phosphate (PLP) phosphatase in Escherichia coli: Importance of PLP homeostasis on the bacterial growth. |
| Contribution Type | Co-authored (other than first author) |
| Journal | The Journal of general and applied microbiology |
| Journal Type | Another Country |
| Volume, Issue, Page | 63(6),pp.362-368 |
| Author and coauthor | Sugimoto Ryota, Saito Natsumi, Shimada Tomohiro, Tanaka Kan |
| Details | The gene ybhA of Escherichia coli encodes a phosphatase that has an in vitro specificity to dephosphorylate pyridoxal 5'-phosphate (PLP or vitamin B6), a co-factor for aminotransferases and other enzymes. In this study, we found that excess pyridoxal (PL) in a minimal medium resulted in excess PLP in vivo and growth inhibition, which was alleviated by YbhA overproduction. Conversely, ... |
| DOI | 10.2323/jgam.2017.02.008 |
| ISSN | 1349-8037 |
| PMID | 29187681 |