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SHIMADA TOMOHIRO
Department Undergraduate School , School of Agriculture Position Associate Professor |
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| Language | English |
| Publication Date | 2020/10 |
| Type | Academic Journal |
| Peer Review | Peer reviewed |
| Title | Expanded roles of pyruvate-sensing PdhR in transcription regulation of the Escherichia coli K-12 genome: fatty acid catabolism and cell motility. |
| Contribution Type | Co-authored (other than first author) |
| Journal | Microbial genomics |
| Journal Type | Another Country |
| Publisher | Microbiology Society |
| Volume, Issue, Page | 6(10) |
| Authorship | Corresponding author |
| Author and coauthor | Takumi Anzai, Sousuke Imamura, Akira Ishihama, Tomohiro Shimada |
| Details | The transcription factor PdhR has been recognized as the master regulator of the pyruvate catabolism pathway in Escherichia coli, including both NAD-linked oxidative decarboxylation of pyruvate to acetyl-CoA by PDHc (pyruvate dehydrogenase complex) and respiratory electron transport of NADH to oxygen by Ndh-CyoABCD enzymes. To identify the whole set of regulatory targets under the control of pyruvate-sensing PdhR, we performed genomic SELEX (gSELEX) screening in vitro. ... |
| DOI | 10.1099/mgen.0.000442 |
| PMID | 32975502 |