|
SHIMADA TOMOHIRO
Department Undergraduate School , School of Agriculture Position Associate Professor |
|
| Language | English |
| Publication Date | 2021 |
| Type | Academic Journal |
| Peer Review | Peer reviewed |
| Title | Single-Target Regulators Constitute the Minority Group of Transcription Factors in Escherichia coli K-12. |
| Contribution Type | Co-authored (first author) |
| Journal | Frontiers in microbiology |
| Journal Type | Another Country |
| Volume, Issue, Page | 12,pp.697803-697803 |
| Authorship | Lead author,Corresponding author |
| Author and coauthor | Tomohiro Shimada, Hiroshi Ogasawara, Ikki Kobayashi, Naoki Kobayashi, Akira Ishihama |
| Details | The identification of regulatory targets of all transcription factors (TFs) is critical for understanding the entire network of genome regulation. A total of approximately 300 TFs exist in the model prokaryote Escherichia coli K-12, but the identification of whole sets of their direct targets is impossible with use of in vivo approaches. For this end, the most direct and quick approach is to identify the TF-binding sites in vitro on the genome. We then developed and utilized the gSELEX screening system ... |
| DOI | 10.3389/fmicb.2021.697803 |
| PMID | 34220787 |