NAKAMURA Takahiro
   Department   Undergraduate School  , School of Agriculture
   Position   Professor
Language English
Publication Date 2021
Type Book Chapter Paper
Title Electrophysiological Approaches to Studying the Suprachiasmatic Nucleus.
Contribution Type Co-authored (other than first author)
Journal Methods in molecular biology (Clifton, N.J.)
Journal TypeAnother Country
Volume, Issue, Page 2130,pp.303-324
International coauthorship International coauthorship
Author and coauthor Michel Stephan, Nakamura Takahiro J, Meijer Johanna H, Colwell Christopher S
Details In mammals, the part of the nervous system responsible for most circadian behavior can be localized to a bilaterally paired structure in the hypothalamus known as the suprachiasmatic nucleus (SCN). Understanding the mammalian circadian system will require a detailed multilevel analysis of neural SCN circuits ex vivo and in vivo. Many of the techniques and approaches that are used for the analysis of the circuitry driving circadian oscillations in the SCN are similar to those employed in other brain regions. There is, however, one fundamental difference that needs to be taken into consideration, that is, the physiological, cell, and molecular properties of SCN neurons vary with the time of day. In this chapter, we will consider the preparations and electrophysiological techniques that we have used to analyze the SCN circuit focusing on the acute brain slice and intact, freely moving animal.
DOI 10.1007/978-1-0716-0381-9_23
ISSN 1940-6029
PMID 33284454