Faculty Database - Takenaka Asako

（Last updated : 2021-08-09 16:55:19）

Takenaka Asako
Department Undergraduate School , School of Agriculture

Position Professor

■ Books and Papers

1.	2018	Article	Effects of eicosapentaenoic acid and docosahexaenoic acid on anxiety-like behavior in socially isolated rats Bioscience, Biotechnology, and Biochemistry 82(4),pp.716-723 (Collaboration)
2.	2018	Article	Importance of Serum Amino Acid Profile for Induction of Hepatic Steatosis under Protein Malnutrition Scientific Reports (Collaboration)
3.	2018	Article	Testosterone represses urinary excretion of the alpha-tocopherol metabolite alpha-carboxymethylhydroxychroman in rats The Journal of Nutritional Biochemistry 62,pp.59-64 (Collaboration)
4.	2017	Article	Branched-chain amino acid supplementation restores reduced insulinotropic activity of a low-protein diet through the vagus nerve in rats Nutrition and Metabolism 14(59),pp.1-12 (Collaboration)
5.	2016	Article	Rapid increase in fibroblast growth factor 2 in protein malnutrition and its impact on growth and lipid metabolism World Biomedical Frontiers (Collaboration)
6.	2015	Article	Rapid increase in fibroblast growth factor 2 in protein malnutrition and its impact on growth and lipid metabolism British Journal of Nutrition 114,pp.1410-1418 (Collaboration)
7.	2014/01	Article	Effects of insulin injection on enhanced insulin receptor substrate-2 (IRS-2) in the liver during dietary protein restriction. Bioscience, Biotechnology, and Biochemistry 78(1),pp.130-138 (Collaboration)
8.	2013/01	Article	Trigonelline Ameliorates Oxidative Stress in Type 2 Diabetic Goto-Kakizaki Rats Journal of Medical Food 16(1),pp.1-8 (Collaboration)
9.	2011/10	Article	Dietary Vitamin E Deficiency Increases Anxiety-Like Behavior in Juvenile and Adult Rats. Biosci. Biotechnol. Biochem. 75(10),pp.1894-1899 (Collaboration)
10.	2010/02	Article	Effect of paraquat-induced oxidative stress on insulin regulation of insulin-like growth factor-binding protein-1 gene expression. J. Clin. Biochem. Nutr. 46(2),pp.157-167 (Collaboration)
11.	2010	Article	Paraquat-induced oxidative stress represses phosphatidylinositol 3-kinase activities leading to impaired glucose uptake in 3T3-L1 adipocytes. J. Biol. Chem. 75(10),pp.1894-1899 (Collaboration)
12.	2009/08	Article	Vitamin E deficiency indreases anxiety-related behavior in rodents. Vitamins pp.477-478 (Single)
13.	2009/05	Article	Dietary vitamin E deficiency increases anxiety-related behavior in rats under stress of social isolation. BioFactors 35(3),pp.273-278 (Collaboration)
14.	2008	Article	Dietary vitamin E deficiency increases anxiety-related behavior in rats. J. Clin. Biochem. Nutr. 43(S1),pp.445-448 (Collaboration)
15.	2007/08	Article	Galactosamine-induced acute liver injury in rats reduces hepatic α-tocopherol transfer protein production. J. Nutr. Sci. Vitaminol. 53(4),pp.366-371 (Collaboration)
16.	2007/01	Article	Effect of various radical generators on insulin-dependent regulation of hepatic gene expression. Bioscience, Biotechnology, and Biochemistry 71(1),pp.16-22 (Collaboration)
17.	2006/04	Article	Soy protein suppresses gene expression of actyl CoA carboxylase from promoter PI in rat liver. Bioscience, Biotechnology, and Biochemistry 70(4),pp.843-849 (Collaboration)
18.	2004	Article	Hepatoprotective activity of tocha, the stems and leaves of Ampelopsis grossedentata, and ampelopsin. Biofactors 21(1-4),pp.175-178 (Collaboration)
19.	2004	Article	Hepatoprotective effects of sesquiterpens in tumeric. Biofactors 21,pp.167-170 (Collaboration)
20.	2003	Article	Preventive effect of dietary nasunin on galactosamine-induced liver injury in rats. Food Science and Technology Research 9(1),pp.94-99 (Collaboration)
21.	2003	Article	Reduction of paraquat-induced oxidative stress in rats by dietary soy peptide. Bioscience, Biotechnology, and Biochemistry 67(2),pp.278-283 (Collaboration)
22.	2002	Article	Soy protein reduces paraquat-induced oxidative stress in rats. Journal of Nutrition 132,pp.2258-2262 (Collaboration)
23.	2001	Article	Protective effects of hot water extract of safflower leaves and its component luteolin-7-O-glucoside on paraquat-induced oxidative stress. Food Science and Technology Research 7,pp.224-230 (Collaboration)
24.	2000	Article	A comparison of the protective effects of between epigallocaechin gallate or epicatechin gallate and the mixtures of their components on paraquat-induced oxidative stress in rats. Food Science and Technology Research 6,pp.146-149 (Collaboration)
25.	2000	Article	Amino acid regulation of gene transcription of rat insulin-like growth factor-binding protein-1. Journal of Endocrinology 164,pp.R11-R16 (Collaboration)
26.	2000	Article	Dietary restriction of single essential amino acids reduces plasma insulin-like growth factor-I (IGF-I) but does not affect plasma IGF-binding protein-1 in rats. Journal of Nutrition 130,pp.2910-2914 (Collaboration)
27.	2000	Article	Preventive effects of dietary cabbage acylated anthocyanins on paraquat-induced oxidative stress in rats. Bioscience, Biotechnology, and Biochemistry 64(8),pp.1600-1607 (Collaboration)
28.	1999	Article	Dexamethasone stabilizes IGFBP-1 mRNA in primary cultures of rat hepatocytes. Endocrine Journal 46,pp.471-476 (Collaboration)
29.	1999	Article	Protective effects of dietary nasunin on paraquat-induced oxidative stress in rats. Bioscience, Biotechnology, and Biochemistry 63,pp.799-804 (Collaboration)
30.	1998	Article	Effect of protein restriction on messenger RNA of insulin-like growth factor-I and insulin-like growth factor-binding proteins in liver of ovariectomized rats. British Journal of Nutrition 79,pp.447-453 (Collaboration)
31.	1998	Article	Insulin-like growth factor-I potentiates protein synthesis induced by thyrotropin in FRTL-5 cells: Comparison of induction of protein synthesis and DNA synthesis. Endocrine Journal 45,pp.151-163 (Collaboration)
32.	1997	Article	Changes in tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 (IRS-1) and ssociation of p85 subunit of phosphatidylinositol 3-kinase with IRS-1 after feeding in rat liver in vivo. Journal of Endocrinology 154,pp.267-273 (Collaboration)
33.	1997	Article	Insulin-like growth factor 1 has beneficial effects, whereas growth hormone has limited effects, on postoperative protein metabolism, gut integrity, and splenic weight in rats with chronic mild liver injury. Journal of Parenteral and Enteral Nutrition 21,pp.55-62 (Collaboration)
34.	1997	Article	Interaction between cAMP-dependent and insulin-dependent signal pathways in tyrosine phosphorylation in primary cultures of rat hepatocytes. Biochemical Journal 324,pp.379-388 (Collaboration)
35.	1997	Article	Starvation-increased Insulin-dependent tyrosine phosphorylation of the 195-kDa protein in intact liver. Bioscience, Biotechnology, and Biochemistry 61,pp.2122-2124 (Collaboration)
36.	1996	Article	Effect of protein nutrition on insulin-like growth factor-I (IGF-I) receptor in various tissues of rats. Journal of Nutritional Science and Vitaminology 42,pp.347-357 (Collaboration)
37.	1996	Article	Effect of protein restriction on the messenger RNA contents of bone-matrix proteins, insulin-like growth factors and insulin-like growth factor binding proteins in femur of ovariectomized rats. British Journal of Nutrition 75,pp.811-823 (Collaboration)
38.	1996	Article	Effects of growth hormone and insulin-like growth factor 1 (IGF-1) on hepatic IGF-1-mRNA, plasma IGF-1 and nitrogen excretion in gastrectomized rats with liver cirrhosis. Clinidal Nutrition 15,pp.321-325 (Collaboration)
39.	1996	Article	Effects of growth hormone and insulin-like growth factor I (IGF-I) treatments on the nitrogen metabolism and hepatic IGF-I-messenger RNA expression in postoperative parenterally fed rats. Journal of Parenteral and Enteral Nutrition, 20,pp.1-7 (Collaboration)
40.	1996	Article	Gene expression of IGF-I and IGF-binding proteins. Journal of Reproduction and Development 42,pp.112-114 (Collaboration)
41.	1996	Article	Nutritional regulation of gene expression of insulin-like growth factor-binding proteins and the acid-labile subunit in various tissues of rats. Journal of Endocrinology 150,pp.33-41 (Collaboration)
42.	1995	Article	Effects of insulin-like growth factor-I, estrogen, glucocorticoid, and transferrin on the mRNA contents of ovalbumin and conalbumin in primary cultures of quail (Coturnix coturnix japonica) oviduct cells. Comparative Biochemistry and Physiology 110C,pp.157-164 (Collaboration)
43.	1995	Article	Production of insulin-like growth factors and their binding proteins in primary cultures of rat liver parenchymal and nonparenchymal cells. Bioscience, Biotechnology, and Biochemistry 59,pp.1503-1515 (Collaboration)
44.	1994	Article	Insulin-like growth factor-I messenger RNA content in the oviduct of Japanese quail (Coturnix coturnix japonica): changes during growth and development or after estrogen administration. Comparative Biochemistry and Physiology, 109C,pp.191-204 (Collaboration)
45.	1994	Article	Relationship between nutrient intake and insulin-like growth factor I (IGF-I). Clinical Pediatric Endocrinology 3,pp.111-114 (Collaboration)
46.	1993	Article	Effect of protein nutrition on the mRNA content of insulin-like growth factor-binding protein-1 in liver and kidney of rats. British Journal of Nutrition 69,pp.73-82 (Collaboration)
47.	1990	Article	A new cDNA clone relating to larger molecular species of rat insulin-like growth factor-I mRNA. Agricultural Biological Chemistry 54,pp.1599-1601 (Collaboration)
48.	1990	Article	Distribution of messenger RNAs of insulin-like growth factor (IGF)-binding proteins-1 and -3 between parenchymal and nonparenchymal cells in rat liver. Agricultural Biological Chemistry 55,pp.1191-1193 (Collaboration)
49.	1990	Article	Evidence of introduction by molecular cloning of artificial inverted sequence at the 5' terminus of the sense strand of rat insulin-like growth factor-I cDNA. Agricultural Biological Chemistry 54,pp.2225-2230 (Collaboration)
50.	1989/02	Book	Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors. pp.125-128 (Collaboration)
51.	1989/02	Book	Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors. (Collaboration)
52.	1989	Article	Dietary and hormonal factors affecting the mRNA level of IGF-I in rat liver in vivo and in primary cultures of rat hepatocytes. D. LeRoith and M. K. Raizada eds.: Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors. Plenum Publishing Corporation. pp.125-128 (Collaboration)
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■ Conference Presentations

1.	2017/10/16	Effect of dietary vitamin E deficiency on social recognition in mice (21st International Congress of Nutrition)
2.	2017/10/16	Mechanism for the decrease in plasma alpha-tocopherol under protein deficiency (21st International Congress of Nutrition)
3.	2015/05/15	Effect of branched-chain amino acids on insulin secretion during feeding (12th Asian Congress of Nutrition)
4.	2015/05/15	Effect of eicosapentaenoic acid on anxiety-like behavior in rats (12th Asian Congress of Nutrition)
5.	2015/05/15	Effect of protein restriction on hepatic uptake of very low-density lipoptrotein (12th Asian Congress of Nutrition)
6.	2015/05/15	Effect of vitamin E deficiency on the hypothalamic-pituitary-adrenal axis in rats (12th Asian Congress of Nutrition)
7.	2015/05/15	Rapid increase of fibroblast growth factor 21 under protein malnutrition and its impact on growth and lipid metabolism (12th Asian Congress of Nutrition)
8.	2014/10/16	Impaired mTORC1 activity up-regulates IGFBP-1 synthesis during dietary protein restriction (The 7th International Congress of the GRS and the IGF Society)
9.	2013/09/17	Sex differences of vitamin E metabolism in rats (20th International Congress of Nutrition)
10.	2012/10	Effect of short-term treatment with insulin on decreased IGF-I expression and increased liver triglycerides during protein deprivation. (The 6th International Congress of the GRS and the IGF Society)
11.	2008/09/17	Role of oxidative stress on the regulation of IGFBP-1 mRNA in protein-deprived rat liver. (The Forth International Congress of the GRS and the IGF Society.)
12.	2007/11	Dietary vitamin E deficiency increases anxiety in rats under stress of social isolation. (International Conference on Food Factors for Health Promotion (ICoFF))
13.	2006/11	An intracellular radical generator, paraquat-induced oxidative stress abolished insulin-dependent repression of IGFBP-1 gene expression in rat hepatocytes. (The Third International Congress of the GRS and the IGF Society)
14.	2006/06	Effect of paraquat-induced oxidative stress on hepatic expression of insulin-responsive genes. (The Endocrine Society's 88th Annual Meeting)
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■ Academic Qualifications

1.	1997/01 Degree Acquisition	The University of Tokyo,
2.	～1990/10	〔Doctorial Course〕 Agricultural Chemistry, Graduate School, Division of Agricultural Science, The University of Tokyo, Unfinished course,
3.	～1990/03	〔Master Course〕 Agricultural Chemistry, Graduate School, Division of Agricultural Science, The University of Tokyo, Completed,
4.	～1988/03	Faculty of Agriculture, The University of Tokyo, Graduated,

■ Current Specialized Field

Food sciences (Key Word：oxidative stress, vitamin E, tocopherol, tocopherol transfer protein, anxiety, behavior, low protein diet)