ISHIMARU YOSHIRO    Department   Undergraduate School  , School of Agriculture    Position   Professor
Research Period	2016/04～2018/03
Research Topic	Obesity induced by collapsed feeding rhythm
Research Type	KAKENHI Research
Consignor	Japan Society for the Promotion of Science
Research Program Type	Grant-in-Aid for Challenging Exploratory Research
KAKENHI Grant No.	16K12746
Responsibility	Collaborative Researcher
Representative Person	OIKE Hideaki
Collaborative Researcher	ISHIMARU Yoshiro
Details	In this study, we analyzed effects of light/dark- or feeding/fasting- pattern on body weight, energy metabolism, and circadian clocks of peripheral tissues in mice. As a result, periodic advance of light/dark cycle efficiently increased body weight gain. Under this light/dark condition, the body weight gain was correlated with decrease of circadian amplitude of respiratory quotient fluctuation and also correlated with glucose usage. It was suggested that collapse of circadian feeding rhythm due to irregular activity pattern caused suppression of lipid usage, leading to obesity.