ISHIMARU YOSHIRO
Department Undergraduate School , School of Agriculture Position Professor |
|
Research Period | 2016/04~2018/03 |
Research Topic | Obesity induced by collapsed feeding rhythm |
Research Type | KAKENHI Research |
Consignor | Japan Society for the Promotion of Science |
Research Program Type | Grant-in-Aid for Challenging Exploratory Research |
KAKENHI Grant No. | 16K12746 |
Responsibility | Collaborative Researcher |
Representative Person | OIKE Hideaki |
Collaborative Researcher | ISHIMARU Yoshiro |
Details | In this study, we analyzed effects of light/dark- or feeding/fasting- pattern on body weight, energy metabolism, and circadian clocks of peripheral tissues in mice. As a result, periodic advance of light/dark cycle efficiently increased body weight gain. Under this light/dark condition, the body weight gain was correlated with decrease of circadian amplitude of respiratory quotient fluctuation and also correlated with glucose usage. It was suggested that collapse of circadian feeding rhythm due to irregular activity pattern caused suppression of lipid usage, leading to obesity. |