シマダ　トモヒロ   SHIMADA TOMOHIRO   島田　友裕    所属   明治大学  農学部    職種   専任准教授
言語種別	英語
発行・発表の年月	2013/02
形態種別	学術雑誌
査読	査読あり
標題	Novel regulator PgrR for switch control of peptidoglycan recycling in Escherichia coli.
執筆形態	共著(筆頭者)
掲載誌名	Genes to cells : devoted to molecular & cellular mechanisms
掲載区分	国外
巻・号・頁	18(2),pp.123-34
担当区分	筆頭著者
著者・共著者	Shimada Tomohiro, Yamazaki Kaoru, Ishihama Akira
概要	Peptidoglycan (PG), also designated as murein, forms a skeletal mesh within the periplasm of bacterial membrane. PG is a metabolically stable cell architecture in Escherichia coli, but under as yet ill-defined conditions, a portion of PG is degraded, of which both amino sugar and peptide moieties are either recycled or used as self-generated nutrients for cell growth. At present, the control of PG degradation remains uncharacterized. Using the Genomic SELEX screening system, we identified an uncharacterized transcription factor YcjZ is a repressor of the expression of the initial step enzymes for PG peptide degradation. ...
DOI	10.1111/gtc.12026
ISSN	1365-2443
PMID	23301696