シマダ トモヒロ   SHIMADA TOMOHIRO
  島田 友裕
   所属   明治大学  農学部
   職種   専任准教授
言語種別 英語
発行・発表の年月 2016/03
形態種別 学術雑誌
査読 査読あり
標題 Transcription profile of Escherichia coli: genomic SELEX search for regulatory targets of transcription factors.
執筆形態 共著(筆頭者以外)
掲載誌名 Nucleic acids research
掲載区分国外
巻・号・頁 44(5),pp.2058-74
著者・共著者 Ishihama Akira, Shimada Tomohiro, Yamazaki Yukiko
概要 Bacterial genomes are transcribed by DNA-dependent RNA polymerase (RNAP), which achieves gene selectivity through interaction with sigma factors that recognize promoters, and transcription factors (TFs) that control the activity and specificity of RNAP holoenzyme. To understand the molecular mechanisms of transcriptional regulation, the identification of regulatory targets is needed for all these factors. We then performed genomic SELEX screenings of targets under the control of each sigma factor and each TF. Here ...
DOI 10.1093/nar/gkw051
ISSN 1362-4962
PMID 26843427