シマダ トモヒロ
SHIMADA TOMOHIRO
島田 友裕 所属 明治大学 農学部 職種 専任准教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2016/03 |
形態種別 | 学術雑誌 |
査読 | 査読あり |
標題 | Transcription profile of Escherichia coli: genomic SELEX search for regulatory targets of transcription factors. |
執筆形態 | 共著(筆頭者以外) |
掲載誌名 | Nucleic acids research |
掲載区分 | 国外 |
巻・号・頁 | 44(5),pp.2058-74 |
著者・共著者 | Ishihama Akira, Shimada Tomohiro, Yamazaki Yukiko |
概要 | Bacterial genomes are transcribed by DNA-dependent RNA polymerase (RNAP), which achieves gene selectivity through interaction with sigma factors that recognize promoters, and transcription factors (TFs) that control the activity and specificity of RNAP holoenzyme. To understand the molecular mechanisms of transcriptional regulation, the identification of regulatory targets is needed for all these factors. We then performed genomic SELEX screenings of targets under the control of each sigma factor and each TF. Here ... |
DOI | 10.1093/nar/gkw051 |
ISSN | 1362-4962 |
PMID | 26843427 |