|
シマダ トモヒロ
SHIMADA TOMOHIRO
島田 友裕 所属 明治大学 農学部 職種 専任准教授 |
|
| 言語種別 | 英語 |
| 発行・発表の年月 | 2017/12 |
| 形態種別 | 学術雑誌 |
| 査読 | 査読あり |
| 標題 | Regulatory role of XynR (YagI) in catabolism of xylonate in Escherichia coli K-12. |
| 執筆形態 | 共著(筆頭者) |
| 掲載誌名 | FEMS microbiology letters |
| 掲載区分 | 国外 |
| 巻・号・頁 | 364(22) |
| 担当区分 | 筆頭著者 |
| 著者・共著者 | Shimada Tomohiro, Momiyama Eri, Yamanaka Yuki, Watanabe Hiroki, Yamamoto Kaneyoshi, Ishihama Akira |
| 概要 | The genome of Escherichia coli K-12 contains ten cryptic phages, altogether constituting about 3.6% of the genome in sequence. Among more than 200 predicted genes in these cryptic phages, 14 putative transcription factor (TF) genes exist, but their regulatory functions remain unidentified. As an initial attempt to make a breakthrough for understanding the regulatory roles of cryptic phage-encoded TFs, we tried to identify the regulatory function of CP4-6 cryptic prophage-encoded YagI with unknown function. After SELEX screening, YagI was found to bind mainly at a single site within the spacer of bidirectional transcription units, yagA (encoding another uncharacterized TF) and yagEF (encoding 2-keto-3-deoxy gluconate aldolase, and dehydratase, respectively) within this prophage region. ... |
| DOI | 10.1093/femsle/fnx220 |
| ISSN | 1574-6968 |
| PMID | 29087459 |