シマダ　トモヒロ   SHIMADA TOMOHIRO   島田　友裕    所属   明治大学  農学部    職種   専任准教授
言語種別	英語
発行・発表の年月	2018/05
形態種別	学術雑誌
査読	査読あり
標題	Single-target regulators form a minor group of transcription factors in Escherichia coli K-12.
執筆形態	共著(筆頭者)
掲載誌名	Nucleic acids research
掲載区分	国外
巻・号・頁	46(8),pp.3921-3936
著者・共著者	Shimada Tomohiro, Ogasawara Hiroshi, Ishihama Akira
概要	The identification of regulatory targets of all TFs is critical for understanding the entire network of the genome regulation. The lac regulon of Escherichia coli K-12 W3110 is composed of the lacZYA operon and its repressor lacI gene, and has long been recognized as the seminal model of transcription regulation in bacteria with only one highly preferred target. After the Genomic SELEX screening in vitro of more than 200 transcription factors (TFs) from E. coli K-12, however, we found that...
DOI	10.1093/nar/gky138
ISSN	1362-4962
PMID	29529243