|
シマダ トモヒロ
SHIMADA TOMOHIRO
島田 友裕 所属 明治大学 農学部 職種 専任准教授 |
|
| 言語種別 | 英語 |
| 発行・発表の年月 | 2018/01 |
| 形態種別 | 学術雑誌 |
| 査読 | 査読あり |
| 標題 | Identification of YbhA as the pyridoxal 5'-phosphate (PLP) phosphatase in Escherichia coli: Importance of PLP homeostasis on the bacterial growth. |
| 執筆形態 | 共著(筆頭者以外) |
| 掲載誌名 | The Journal of general and applied microbiology |
| 掲載区分 | 国外 |
| 巻・号・頁 | 63(6),pp.362-368 |
| 著者・共著者 | Sugimoto Ryota, Saito Natsumi, Shimada Tomohiro, Tanaka Kan |
| 概要 | The gene ybhA of Escherichia coli encodes a phosphatase that has an in vitro specificity to dephosphorylate pyridoxal 5'-phosphate (PLP or vitamin B6), a co-factor for aminotransferases and other enzymes. In this study, we found that excess pyridoxal (PL) in a minimal medium resulted in excess PLP in vivo and growth inhibition, which was alleviated by YbhA overproduction. Conversely, ... |
| DOI | 10.2323/jgam.2017.02.008 |
| ISSN | 1349-8037 |
| PMID | 29187681 |