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シマダ トモヒロ
SHIMADA TOMOHIRO
島田 友裕 所属 明治大学 農学部 職種 専任教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2020/10 |
| 形態種別 | 学術雑誌 |
| 査読 | 査読あり |
| 標題 | Expanded roles of pyruvate-sensing PdhR in transcription regulation of the Escherichia coli K-12 genome: fatty acid catabolism and cell motility. |
| 執筆形態 | 共著(筆頭者以外) |
| 掲載誌名 | Microbial genomics |
| 掲載区分 | 国外 |
| 出版社・発行元 | Microbiology Society |
| 巻・号・頁 | 6(10) |
| 担当区分 | 責任著者 |
| 著者・共著者 | Takumi Anzai, Sousuke Imamura, Akira Ishihama, Tomohiro Shimada |
| 概要 | The transcription factor PdhR has been recognized as the master regulator of the pyruvate catabolism pathway in Escherichia coli, including both NAD-linked oxidative decarboxylation of pyruvate to acetyl-CoA by PDHc (pyruvate dehydrogenase complex) and respiratory electron transport of NADH to oxygen by Ndh-CyoABCD enzymes. To identify the whole set of regulatory targets under the control of pyruvate-sensing PdhR, we performed genomic SELEX (gSELEX) screening in vitro. ... |
| DOI | 10.1099/mgen.0.000442 |
| PMID | 32975502 |