シマダ トモヒロ
SHIMADA TOMOHIRO
島田 友裕 所属 明治大学 農学部 職種 専任准教授 |
|
言語種別 | 英語 |
発行・発表の年月 | 2020/10 |
形態種別 | 学術雑誌 |
査読 | 査読あり |
標題 | Expanded roles of pyruvate-sensing PdhR in transcription regulation of the Escherichia coli K-12 genome: fatty acid catabolism and cell motility. |
執筆形態 | 共著(筆頭者以外) |
掲載誌名 | Microbial genomics |
掲載区分 | 国外 |
出版社・発行元 | Microbiology Society |
巻・号・頁 | 6(10) |
担当区分 | 責任著者 |
著者・共著者 | Takumi Anzai, Sousuke Imamura, Akira Ishihama, Tomohiro Shimada |
概要 | The transcription factor PdhR has been recognized as the master regulator of the pyruvate catabolism pathway in Escherichia coli, including both NAD-linked oxidative decarboxylation of pyruvate to acetyl-CoA by PDHc (pyruvate dehydrogenase complex) and respiratory electron transport of NADH to oxygen by Ndh-CyoABCD enzymes. To identify the whole set of regulatory targets under the control of pyruvate-sensing PdhR, we performed genomic SELEX (gSELEX) screening in vitro. ... |
DOI | 10.1099/mgen.0.000442 |
PMID | 32975502 |