シマダ トモヒロ
SHIMADA TOMOHIRO
島田 友裕 所属 明治大学 農学部 職種 専任准教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2021 |
形態種別 | 学術雑誌 |
査読 | 査読あり |
標題 | Single-Target Regulators Constitute the Minority Group of Transcription Factors in Escherichia coli K-12. |
執筆形態 | 共著(筆頭者) |
掲載誌名 | Frontiers in microbiology |
掲載区分 | 国外 |
巻・号・頁 | 12,pp.697803-697803 |
担当区分 | 筆頭著者,責任著者 |
著者・共著者 | Tomohiro Shimada, Hiroshi Ogasawara, Ikki Kobayashi, Naoki Kobayashi, Akira Ishihama |
概要 | The identification of regulatory targets of all transcription factors (TFs) is critical for understanding the entire network of genome regulation. A total of approximately 300 TFs exist in the model prokaryote Escherichia coli K-12, but the identification of whole sets of their direct targets is impossible with use of in vivo approaches. For this end, the most direct and quick approach is to identify the TF-binding sites in vitro on the genome. We then developed and utilized the gSELEX screening system ... |
DOI | 10.3389/fmicb.2021.697803 |
PMID | 34220787 |