サトウ　バン   SATO BAN   佐藤　伴    所属   明治大学  農学部    職種   助教
言語種別	英語
発行・発表の年月	2023/03
形態種別	学術雑誌
査読	査読あり
招待論文	招待あり
標題	Proteasome-Associated Proteins, PA200 and ECPAS, Are Essential for Murine Spermatogenesis
執筆形態	共著(筆頭者)
掲載誌名	Biomolecules
掲載区分	国外
出版社・発行元	MDPI AG
巻・号・頁	13(4),pp.586-586
担当区分	筆頭著者,責任著者
著者・共著者	◎Ban Sato,Jiwoo Kim,Kazunori Morohoshi,Woojin Kang,Kenji Miyado,Fuminori Tsuruta,Natsuko Kawano,Tomoki Chiba
概要	Proteasomes are highly sophisticated protease complexes that degrade non-lysosomal proteins, and their proper regulation ensures various biological functions such as spermatogenesis. The proteasome-associated proteins, PA200 and ECPAS, are predicted to function during spermatogenesis; however, male mice lacking each of these genes sustain fertility, raising the possibility that these proteins complement each other. Our results indicate that PA200 and ECPAS work cooperatively during spermatogenesis and are essential for male fertility.
DOI	10.3390/biom13040586
ISSN	/2218-273X
PermalinkURL	https://www.mdpi.com/2218-273X/13/4/586/pdf