オノ　ユミエ   ONO YUMIE   小野　弓絵    所属   明治大学  理工学部    職種   専任教授
言語種別	英語
発行・発表の年月	2019/02
形態種別	学術雑誌
査読	査読あり
標題	Development of a brain-machine interface for stroke rehabilitation using event-related desynchronization and proprioceptive feedback
執筆形態	共著(筆頭者以外)
掲載誌名	Advanced Biomedical Engineering
掲載区分	国外
出版社・発行元	Japanese Society for Medical and Biological Engineering
巻・号・頁	8,pp.53-59
著者・共著者	K. Wada, Y. Ono, M. Kurata, M. I. Ito, M. T. Minakuchi, M. Kono, T. Tominaga
概要	We have developed a brain-machine interface (BMI) rehabilitation system for patients with stroke and motor paralysis that provides proprioceptive feedback upon successful generation of motor-imagery (MI)-induced event-related desynchronization (ERD), and a decrease in mu band (8-13 Hz) activity derived from hand motor imagery. This system consists of an electroencephalogram (EEG) amplifier, operated using the MATLAB Simulink software, a pneumatic robotic exoskeleton to provide proprioceptive feedback to the paralyzed hand, and a tablet computer placed over the paralyzed hand to display a hand-action movie to facilitate ERD generation. The EEG amplifier was connected and synchronized via the exoskeleton and tablet computer with an Arduino microcomputer. Nine patients with stroke in sub-acute stage of recovery participated in a neurofeedback training experiment, which employed the above-mentioned system. During the 4 weeks of this study, the participants received 2 weeks of Digital Mirror Box (DMB)-based or control interventions in a random and counterbalanced order in addition to their daily conventional physiotherapy. The control intervention consisted of the same MI training as the DMB-based intervention, but the exoskeleton always provided proprioceptive feedback regardless of their ERD strength. The ERD strength in the affected hemisphere showed a desirable increase with significant improvement of finger joint spasticity only after the DMB-based intervention period and not after the control intervention period. The proposed neurofeedback training can help patients with stroke and movement disorders because increased ERD strength may lead to recovery of motor function.
researchmap用URL	https://doi.org/10.14326/abe.8.53