シマダ　トモヒロ   SHIMADA TOMOHIRO   島田　友裕    所属   明治大学  農学部    職種   専任准教授
言語種別	英語
発行・発表の年月	2008/09
形態種別	学術雑誌
査読	査読あり
標題	The uncharacterized transcription factor YdhM is the regulator of the nemA gene, encoding N-ethylmaleimide reductase.
執筆形態	共著(筆頭者以外)
掲載誌名	Journal of bacteriology
掲載区分	国外
巻・号・頁	190(17),pp.5890-7
著者・共著者	Umezawa Yoshimasa, Shimada Tomohiro, Kori Ayako, Yamada Kayoko, Ishihama Akira
概要	N-ethylmaleimide (NEM) has been used as a specific reagent of Cys modification in proteins and thus is toxic for cell growth. On the Escherichia coli genome, the nemA gene coding for NEM reductase is located downstream of the gene encoding an as-yet-uncharacterized transcription factor, YdhM. Disruption of the ydhM gene results in reduction of nemA expression even in the induced state, indicating that the two genes form a single operon. After in vitro genomic SELEX screening, ...
DOI	10.1128/JB.00459-08
ISSN	1098-5530
PMID	18567656