ササキ　ヨウスケ   SASAKI YOSUKE   佐々木　羊介    所属   明治大学  農学部    職種   専任准教授
言語種別	英語
発行・発表の年月	2019/09
形態種別	学術雑誌
査読	査読あり
標題	Total serum protein reference value as a clinical diagnostic index of equine proliferative enteropathy.
執筆形態	共著(筆頭者以外)
掲載誌名	Journal of equine science
掲載区分	国外
巻・号・頁	30(3),pp.63-67
著者・共著者	Yasushi Ueno, Ryoko Uemura, Hidekazu Niwa, Toru Higuchi, Satoshi Sekiguchi, Yosuke Sasaki, Masuo Sueyoshi
概要	Equine proliferative enteropathy (EPE) caused by Lawsonia intracellularis is characterized by hypoproteinemia. There are currently no reliable reports that provide a reference value for the total serum protein (TP) concentration to clinically diagnose EPE. The objective of this study was to statistically determine the reference value. Feces and sera of 99 foals with EPE-like clinical signs and of 35 healthy foals were obtained. The samples were used for specific-gene detection of L. intracellularis, TP measurement, and specific-antibody detection against L. intracellularis. Based on these results, the optimal reference value for the TP concentration as a clinical diagnostic index of EPE was found to be ≤ 4.8 g/dl. This clinical diagnostic index will provide an effective approach for diagnosing EPE.
DOI	10.1294/jes.30.63
PMID	31592224