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シマダ トモヒロ
SHIMADA TOMOHIRO
島田 友裕 所属 明治大学 農学部 職種 専任准教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2014/08 |
| 形態種別 | 学術雑誌 |
| 査読 | 査読あり |
| 標題 | Intracellular concentrations of 65 species of transcription factors with known regulatory functions in Escherichia coli. |
| 執筆形態 | 共著(筆頭者以外) |
| 掲載誌名 | Journal of bacteriology |
| 掲載区分 | 国外 |
| 巻・号・頁 | 196(15),pp.2718-27 |
| 著者・共著者 | Ishihama Akira, Kori Ayako, Koshio Etsuko, Yamada Kayoko, Maeda Hiroto, Shimada Tomohiro, Makinoshima Hideki, Iwata Akira, Fujita Nobuyuki |
| 概要 | The expression pattern of the Escherichia coli genome is controlled in part by regulating the utilization of a limited number of RNA polymerases among a total of its approximately 4,600 genes. The distribution pattern of RNA polymerase changes from modulation of two types of protein-protein interactions: the interaction of core RNA polymerase with seven species of the sigma subunit for differential promoter recognition and the interaction of RNA polymerase holoenzyme with about 300 different species of transcription factors (TFs) with regulatory functions. We have been involved in the systematic search for the target promoters recognized by each sigma factor and each TF using the newly developed Genomic SELEX system. In parallel, ... |
| DOI | 10.1128/JB.01579-14 |
| ISSN | 1098-5530 |
| PMID | 24837290 |