シマダ トモヒロ   SHIMADA TOMOHIRO
  島田 友裕
   所属   明治大学  農学部
   職種   専任准教授
言語種別 英語
発行・発表の年月 2015/11
形態種別 学術雑誌
査読 査読あり
標題 Expanded roles of two-component response regulator OmpR in Escherichia coli: genomic SELEX search for novel regulation targets.
執筆形態 共著(筆頭者)
掲載誌名 Genes to cells : devoted to molecular & cellular mechanisms
掲載区分国外
巻・号・頁 20(11),pp.915-31
担当区分 筆頭著者
著者・共著者 Shimada Tomohiro, Takada Hiraku, Yamamoto Kaneyoshi, Ishihama Akira
概要 The two-component system (TCS) is a sophisticated bacterial signal transduction system for regulation of genome transcription in response to environmental conditions. The EnvZ-OmpR system is one of the well-characterized TCS of Escherichia coli, responding to changes in environmental osmolality. Regulation has largely focused on the differential expression of two porins, OmpF and OmpC, which transport small molecules across the outer membrane. Recently, it has become apparent that OmpR serves a more global regulatory role and regulates additional targets. To identify the entire set of regulatory targets of OmpR, we performed ...
DOI 10.1111/gtc.12282
ISSN 1365-2443
PMID 26332955