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シマダ トモヒロ
SHIMADA TOMOHIRO
島田 友裕 所属 明治大学 農学部 職種 専任准教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2017/07 |
| 形態種別 | 学術雑誌 |
| 査読 | 査読あり |
| 標題 | A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation. |
| 執筆形態 | 共著(筆頭者以外) |
| 掲載誌名 | FEBS letters |
| 掲載区分 | 国外 |
| 巻・号・頁 | 591(13),pp.2019-2031 |
| 著者・共著者 | Sugino Hirotaka, Usui Takanori, Shimada Tomohiro, Nakano Masahiro, Ogasawara Hiroshi, Ishihama Akira, Hirata Akira |
| 概要 | RcdA is a regulator of curlin subunit gene D, the master regulator of biofilm formation in Escherichia coli. Here, we determined the X-ray structure of RcdA at 2.55 Å resolution. RcdA consists of an N-terminal DNA-binding domain (DBD) containing a helix-turn-helix (HTH) motif and a C-terminal dimerization domain, and forms a homodimer in crystals. A computational docking model of the RcdA-DNA complex allowed prediction of the candidate residues responsible for DNA binding. ... |
| DOI | 10.1002/1873-3468.12713 |
| ISSN | 1873-3468 |
| PMID | 28608551 |