SHIMADA TOMOHIRO
Department Undergraduate School , School of Agriculture Position Associate Professor |
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Language | English |
Publication Date | 2018/01 |
Type | Academic Journal |
Peer Review | Peer reviewed |
Title | Identification of YbhA as the pyridoxal 5'-phosphate (PLP) phosphatase in Escherichia coli: Importance of PLP homeostasis on the bacterial growth. |
Contribution Type | Co-authored (other than first author) |
Journal | The Journal of general and applied microbiology |
Journal Type | Another Country |
Volume, Issue, Page | 63(6),pp.362-368 |
Author and coauthor | Sugimoto Ryota, Saito Natsumi, Shimada Tomohiro, Tanaka Kan |
Details | The gene ybhA of Escherichia coli encodes a phosphatase that has an in vitro specificity to dephosphorylate pyridoxal 5'-phosphate (PLP or vitamin B6), a co-factor for aminotransferases and other enzymes. In this study, we found that excess pyridoxal (PL) in a minimal medium resulted in excess PLP in vivo and growth inhibition, which was alleviated by YbhA overproduction. Conversely, ... |
DOI | 10.2323/jgam.2017.02.008 |
ISSN | 1349-8037 |
PMID | 29187681 |