シマダ トモヒロ   SHIMADA TOMOHIRO
  島田 友裕
   所属   明治大学  農学部
   職種   専任准教授
言語種別 英語
発行・発表の年月 2020/10
形態種別 学術雑誌
査読 査読あり
標題 Expanded roles of pyruvate-sensing PdhR in transcription regulation of the Escherichia coli K-12 genome: fatty acid catabolism and cell motility.
執筆形態 共著(筆頭者以外)
掲載誌名 Microbial genomics
掲載区分国外
出版社・発行元 Microbiology Society
巻・号・頁 6(10)
担当区分 責任著者
著者・共著者 Takumi Anzai, Sousuke Imamura, Akira Ishihama, Tomohiro Shimada
概要 The transcription factor PdhR has been recognized as the master regulator of the pyruvate catabolism pathway in Escherichia coli, including both NAD-linked oxidative decarboxylation of pyruvate to acetyl-CoA by PDHc (pyruvate dehydrogenase complex) and respiratory electron transport of NADH to oxygen by Ndh-CyoABCD enzymes. To identify the whole set of regulatory targets under the control of pyruvate-sensing PdhR, we performed genomic SELEX (gSELEX) screening in vitro. ...
DOI 10.1099/mgen.0.000442
PMID 32975502