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SATO BAN
Department Undergraduate School , School of Agriculture Position Assistant Professor |
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| Language | English |
| Publication Date | 2023/03 |
| Type | Academic Journal |
| Peer Review | Peer reviewed |
| Invitation | Invited paper |
| Title | Proteasome-Associated Proteins, PA200 and ECPAS, Are Essential for Murine Spermatogenesis |
| Contribution Type | Co-authored (first author) |
| Journal | Biomolecules |
| Journal Type | Another Country |
| Publisher | MDPI AG |
| Volume, Issue, Page | 13(4),pp.586-586 |
| Authorship | Lead author,Corresponding author |
| Author and coauthor | ◎Ban Sato,Jiwoo Kim,Kazunori Morohoshi,Woojin Kang,Kenji Miyado,Fuminori Tsuruta,Natsuko Kawano,Tomoki Chiba |
| Details | Proteasomes are highly sophisticated protease complexes that degrade non-lysosomal proteins, and their proper regulation ensures various biological functions such as spermatogenesis. The proteasome-associated proteins, PA200 and ECPAS, are predicted to function during spermatogenesis; however, male mice lacking each of these genes sustain fertility, raising the possibility that these proteins complement each other. Our results indicate that PA200 and ECPAS work cooperatively during spermatogenesis and are essential for male fertility. |
| DOI | 10.3390/biom13040586 |
| ISSN | /2218-273X |
| PermalinkURL | https://www.mdpi.com/2218-273X/13/4/586/pdf |