カワノ　ナツコ   KAWANO NATSUKO   河野　菜摘子    所属   明治大学  農学部    職種   専任准教授
言語種別	英語
発行・発表の年月	2017
形態種別	学術雑誌
査読	査読あり
招待論文	招待あり
標題	Exosomes versus microexosomes: Shared components but distinct functions
執筆形態	共著(編集/監修)
掲載誌名	Journal of Plant Research
掲載区分	国外
出版社・発行元	Springer
巻・号・頁	130(3),pp.479-483
著者・共著者	Miyado K, Kang W, Yamatoya K, Hanai M, Nakamura A, Mori T, Miyado M, Kawano N.
概要	In multicellular organisms, cellular components are constantly translocated within cells and are also transported exclusively between limited cells, regardless of their physical distance. Exosomes function as one of the key mediators of intercellular transportation. External vesicles were identified 50 years ago in plants and now reconsidered to be exosome-like vesicles. Meanwhile, a well-known exosomal component, tetraspanin CD9, regulates sperm-egg fusion in mammals. A number of Arabidopsis tetraspanins are also expressed in reproductive tissues at fertilization, and are localized at the plasma membrane of protoplasts. Moreover, CD9-containing structures (or 'microexosomes') are released from mouse eggs during their maturation and promote the sperm-egg fusion. This phenomenon implies that two types of shared-component intercellular carriers might be released from multiple types of plant and animal cells, which widely regulate biological phenomena. We herein highlight their discrete structures, formation processes, and functions.
DOI	doi:10.1007/s10265-017-0907-7