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(最終更新日:2015-02-14 16:38:32.983)
ササキ タカノリ
SASAKI Takanori
佐々木 貴規
所属
明治大学 総合数理学部
職種
専任准教授
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著書・論文
1.
2012/10
論文
pH-dependent interaction between membrane and histidine- containing peptides Chemistry Letters 41(10),pp.1193-1195 (共著)
2.
2012/07
論文
Vertically oriented α-helical peptides in Langmuir-Blodgett films e-Journal of Surface Science and Nanotechnology 10,pp.379-387 (共著)
3.
2012/06
論文
Homotrimer formation and dissociation of pharaonis halorhodopsin in detergent system Biophysical journal 102(12),pp.2906-2915 (共著)
4.
2012/02
論文
Characteristics of halorhodopsin-bacterioruberin complex from Natronomonas pharaonis membrane in the solubilized system Biochemistry 51(13),pp.2785-2794 (共著)
5.
2012/01
論文
Fabrication of langmuir-blodgett films using amphiphilic peptides Nanoscience and Nanotechnology 12(1),pp.568-572 (共著)
6.
2012
論文
A computational identification method for GPI-anchored proteins by artificial neural network Current Bioinformatics 7(2),pp.125-131 (共著)
7.
2011/05
論文
Discrimination of Golgi type II membrane proteins focusing on thier membrane spanning peptide sequences Proceedings of the 5th International Peptide Symposium (共著)
8.
2011/05
論文
Discrimination of GPI-anchored proteins using artificial neural network Proceedings of the 5th International Peptide Symposium (共著)
9.
2011/02
論文
Sensitive detection of protein-lipid interaction change on bacteriorhodopsin using dodecyl β-D-maltoside Biochemistry 50(12),pp.2283-2290 (共著)
10.
2011
論文
Discrimination of golgi type II membrane proteins based on their hydropathy profiles and the amino acid propensities of their transmembrane regions Bioscience, Biotechnology, and Biochemistry 75 (共著)
11.
2011
論文
Fabrication of langmuir-blodgett films using amphiphilic peptides Journal of Nanoscience and Nanotechnology (共著)
12.
2010/12
論文
A discrimination method for golgi type II membrane proteins based on the hydropathy alignment and the position-specific score matrix around their transmembrane regions Proceedings of the 2nd international conference on Trendz in information sciences and computing pp.82-87 (共著)
13.
2010/12
論文
Development a database of genome-wide GPI-anchored proteins Proceedings of the 2nd international conference on Trendz in information sciences and computing pp.110-112 (共著)
14.
2010/12
論文
Identification of mammalian GPI-anchored proteins based on amino acid propensities in their GPI attachment signal sequences Proceedings of the 2nd international conference on Trendz in information sciences and computing pp.113-117 (共著)
15.
2009/11
論文
Effect of chloride binding on the thermal trimer-monomer conversion of halorhodopsin in the solubilized system Biochemistry 48(51),pp.12089-12095 (共著)
16.
2009/11
論文
Electrophoresis of dyes and proteins in poly(acrylamide) gel containing immobilized bilayer membranes Progress in Colloid and Polymer Science 136,pp.143-148 (共著)
17.
2009/07
論文
Identification of GPI-anchored proteins using position specific score matrix FEBS Journal 276(1),pp.126-127 (共著)
18.
2009/01
論文
Halorhodopsin from Natronomonas pharaonis forms a trimer even in the presence of a detergent, Dodecyl-β-D-maltoside Photochemistry and Photobiology (85),pp.130-136 (共著)
19.
2005/08
論文
Hydrogen-Bonding Alterations of the Protonated Schiff Base and Water Molecule in the Chloride Pump of Natronobacterium pharaonis Biochemistry. (44(37)),pp.12279-12286 (共著)
20.
2005/06
論文
Photobleaching of bacteriorhodopsin solubilized with TritonX-100 Photochemistry and Photobiology (81),pp.1131-1137 (共著)
21.
2004/04
論文
Internal Water Molecules of Light-Driven Chloride Pump Proteins chemical physics letters (392),pp.330-333 (共著)
22.
2002/08
論文
Structural Stability of Bacteriorhodopsin Solubilized by Triton X-100 Journal of Photoscience (9),pp.293-295 (共著)
5件表示
全件表示(22件)
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学会発表
1.
2012/09
Features of halorhodopsin-carotenoid complex from Natronomonas pharaonis membrane in the solubilized system(37th FEBS Congress)
2.
2012/09
Formation of a complex between membrane protein halorhodopsin and carotenoid of bacterioruberin in the solubilized system(The 50th Annual Meeting of the Biophysical Society of Japan)
3.
2012/06
ドデシルマルトシドにより可溶化されたファラオニスハロロドプシンが持つカロテノイド結合能(第12回日本蛋白質科学会年会)
4.
2011/09
Correlation between the disaccharide structures of alkyl glycosides and the structural stability of solubilized membrane protein(The 49th Annual Meeting of the Biophysical Society of Japan)
5.
2011/09
Langmuir-Blodgett法による両親媒性ペプチドの構造および配列制御(第72回応用物理学会学術講演会)
6.
2011/06
ファラオニスハロロドプシンの三量体会合強度に関与するアニオン結合部位の同定(第11回日本蛋白質科学会年会)
7.
2011/06
界面活性剤ドデシルマルトシドを用いた膜タンパク質バクテリオロドプシン-脂質間相互作用変化の敏感な検出(第11回日本蛋白質科学会年会)
8.
2011/06
逆誤差伝播型ニューラルネットワークによるGPIアンカー型タンパク質の判別方法(第11回日本蛋白質科学会年会)
9.
2011/03
Correlation between molecular area and solubilizing ability for membrane protein on detergent molecule(Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry)
10.
2010/09
Correlation between tertiary structure and solubility in Dodecyl-β-D-maltoside on membrane protein bacteriorhodopsin(The 48th Annual Meeting of the Biophysical Society of Japan)
11.
2010/08
Trimer formation of N.pharaonis Halorhodopsin is stabilized by the intermolecular interaction among Phe150 residue and leads to functional modulation in detergent solution(14th International Conference on Retinal Proteins)
12.
2010/06
Detection of the ligand binding/release state of membrane protein bacteriorhodopsin by the change of solubility in Dodecyl-β-D-maltoside(35th FEBS Congress)
13.
2010/06
膜タンパク質バクテリオロドプシンのリガンド結合・解離と非イオン性界面活性剤ドデシルマルトシドに対する可溶性の関係(第10回日本蛋白質科学会年会)
14.
2009/10
Stabilization of trimeric assembly of halorhodopsin, NpHR by C3-symmetric geometry among F150 aromatic rings(The 47th Annual Meeting of the Biophysical Society of Japan)
15.
2009/07
Computational detection of GPI-anchored proteins using hydropathy profile and PSSM(EUROCARB 2009 (15th European Carbohydrate Symposium))
16.
2009/07
Identification of GPI-anchored proteins using position specific score matrix(34th FEBS Congress)
17.
2008/12
Is the photoactivity of halorhodopsin modulated by the assembly of homotrimer ?(The 46th Annual Meeting of the Biophysical Society of Japan)
18.
2008/06
Trimer assembly of Natronomonas Pharaonis halorhodopsin, NphR in lipid bilayer and detergent(13th International Conference on Retinal Proteins)
19.
2007/01
The change of trimer packing intensity of halorhodopsin caused by binding or release of Cl- ion(9th Hokkaido University-Seoul National University Joint Symposium Satellite Session)
20.
2007/01
Visual spectral shift of halorhodopsin in pH titration(9th Hokkaido University-Seoul National University Joint Symposium Satellite Session)
21.
2006/11
Structural network in the extracellular region corresponding to the visual spectral shift of halorhodopsin(Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ))
22.
2006/11
The Change of trimer packing intensity of halorhodopsin caused by binding or release of Cl- ion(Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ))
23.
2006/11
The role of E234 on the extracellular site in the anion pump of pharaonis halorhodopsin(Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ). Okinawa Convention Center, Okinawa, Japan)
24.
2006/11
Trimer-monomer conversion of pharaonis halorhodopsin by anion binding(Fifth East Asian Biophysics Symposium and Forty-Fourth Annual Meeting of the Biophysical Society of Japan (EABS and BSJ))
25.
2006/06
Effects of EC-channel residues, E234 and R176, of pharaonis halorhodopsin on structural stability and functions(12th International Conference on Retinal Proteins (12/ ICPR))
26.
2006/06
Functional and structural role of trimer paking of pharaonis halorhodopsin,(12th International Conference on Retinal Proteins (12/ICPR))
27.
2006/06
Inversion of spectral shifts of pharaonis halorhodopsin in anion titration caused by changing pH(12th International Conference on Retinal Proteins (12/ ICPR))
28.
2006/04
古細菌ロドプシンの吸収波長シフト方向を決定する構造因子(第6回蛋白質科学会年会)
29.
2006/03
膜タンパク質ハロロドプシンはなぜトリマー形成するのか?(日本生物物理学会北海道支部例会)
30.
2005/11
The correlation between anion binding and the mechanism of oligomer formation for membrane protein halorhodopsin(日本生物物理学会 第43回日本生物物理学会年会)
31.
2005/11
プロトンをポンプするアジド結合型ハロロドプシンの低温赤外分光(日本生物物理学会 第43回日本生物物理学会年会)
32.
2005/09
膜タンパク質ハロロドプシンのオリゴマー構造形成メカニズム(特定領域研究「生体超分子の構造形成と機能制御の原子機構」第一回ワークショップ)
33.
2005/06
ファラオニスハロロドプシンのアニオン結合と集積構造形成(分子科学研究所研究会「ロドプシンの仲間・G蛋白質共役型レセプターの機能と構造)
34.
2005/06
脱塩状態における膜タンパク質ハロロドプシンの退色と集積構造崩壊(日本蛋白質科学会 第5回日本蛋白質科学会年会)
35.
2005/03
膜タンパク質ハロロドプシンのアニオン結合と自己組織化構造(北海道21世紀COEプログラム「バイオとナノを融合する新生命科学拠点」第六回 COE大学院生主催研究発表会)
36.
2004/12
界面活性剤Triton X-100がファラオニスハロロドプシンのシッフ塩基結合、2次元結晶構造に与える影響に関して(第42回日本生物物理学会年会)
37.
2004/07
光駆動塩素イオンポンプ蛋白質、ハロロドプシン(HR)中の内部結合水の構造解析(第31回生体分子化学討論会)
38.
2004/04
Chloride ion promotes Retinal binding to halo-opsin in Triton X-100(The 1st Pacific-Rim International Conference on Protein Science (PRICP))
39.
2003/06
界面活性剤Triton X-100による可溶化バクテリオロドプシンの構造安定性について(第3回日本蛋白質科学会年会)
40.
2002/11
Triton X-100による可溶化バクテリオロドプシンの光誘起変性(第40回日本生物物理学会年会)
41.
2002/06
Structural stability of bacteriorhodopsin solubilized by Triton X-100(1st Asian Conference on Photobiology)
42.
2002/01
界面活性剤Triton X-100による可溶化バクテリオロドプシンの構造安定性(特定領域研究C「ゲノム情報科学の進展開」公開シンポジウム)
43.
1999/11
可視領域におけるバクテリオロドプシンのCDスペクトルが示す多様性(第6回日本光生物学協会講演会)
44.
1999/05
バクテリオロドプシンの立体構造安定性における二次元結晶構造の効果-Ⅱ. オクチルグルコシド、ドデシルマルトシド、Triton X-100 による可溶化の比較(第11回日本蛋白質工学会年会)
5件表示
全件表示(44件)
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学歴
1.
~2007/03
北海道大学 理学研究科 博士課程修了 博士(理学)
2.
2002/03
(学位取得)
東京農工大学 修士(工学)
3.
~1999/03
東京農工大学 工学部 卒業
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所属学会
1.
日本生物物理学会
2.
日本蛋白質科学会
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社会における活動
1.
2007/04~2008/03
PDBj-BMRB(生体高分子のNMRデータベース編集)グループメンバー
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研究課題・受託研究・科研費
1.
固体NMRスペクトルの信号帰属自動化アルゴリズム開発
2.
膜蛋白質古細菌ロドプシンの物性調査
3.
2013/04~2016/03
光受容体膜タンパク質ハロロドプシンに対するカロテノイド色素の結合メカニズム解明 若手研究 (B)
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受賞学術賞
1.
2006
財団法人北海道大学クラーク記念財団博士課程在学生研究助成