Faculty Database - KAWAGUCHI Maiko

Books and Papers

Conference Presentations

Academic Qualifications

researchmap Researcher Code

Certificates and Licenses

Web Sites

Current Specialized Field

（Last updated : 2025-10-18 10:00:57）

KAWAGUCHI Maiko
Department Undergraduate School , School of Agriculture

Position Associate Professor

■ Books and Papers

1.	2025/06	Article	Candidate Anxiety-Related Genes in the Hippocampus of Hatano Male Rats: Anxiolytic Action of Neuromedin U in the Hippocampus Neuropsychopharmacology Reports 45(2) (Collaboration)
2.	2025/03	Article	Administration of a Selective Antagonist for Pituitary Adenylate Cyclase‐Activating Polypeptide Receptor in the Hippocampus Causes Anxiolytic Effects in the Male Rat Neuropsychopharmacology Reports 45(1) (Collaboration)
3.	2023/03	Article	Bidirectional effects of voluntary exercise on the expression of Bdnf isoforms in the hippocampus of Hatano rat strains displaying different activity levels Neuropsychopharmacology Reports (Collaboration)
4.	2022/09	Article	Toxicological effects of Tris (1,3-dichloro-2-propyl) phosphate exposure in adult male rats differ depending on the history of exposure in the neonatal period Journal of applied toxicology 42(9),pp.1503-1509 (Collaboration)
5.	2022/06	Article	Possible effects of voluntary exercise intensity on anxiety-like behavior and its underlying molecular mechanisms in the hippocampus: Results from a study in Hatano rats. Behavioural Brain Research 427,pp.113854-113854 (Collaboration)
6.	2022/03	Article	Alterations between high and low-avoidance lines of Hatano rats in learning behaviors, ultrasonic vocalizations, and histological characteristics in hippocampus and amygdala. Physiology & Behavior 245 (Collaboration)
7.	2022/01	Article	Effects of tris(1,3-dichloro-2-propyl) phosphate on epididymal sperm parameters in adult male rats The Journal of veterinary medical science 84(1),pp.153-156 (Collaboration)
8.	2021/10	Article	Impact of dietary exposure to low-dose tris(1,3-dichloro-2-propyl)phosphate in allergic asthmatic mice Immunopharmacol Immunotoxicol. 43(5),pp.599-610 (Collaboration)
9.	2021/06	Article	Novel toxicity of tris (1,3-dichloro-2-propyl) phisphate in adult male rats. Journal of Applied Toxicology 41(6),pp.987-992 (Collaboration)
10.	2021/02	Article	Maternal traits during lactation period reduce the anxiety-related behavior in male offspring: Results from a fostering study in Hatano rats Physiology & Behavior 229 (Collaboration)
11.	2020/11	Article	Investigating the effects of nest shading on the green turtle (Chelonia mydas) hatchling phenotype in the Ogasawara islands using a field-based split clutch experiment Journal of Experimental Zoology Part A: Ecological and Integrative Physiology 333(9),pp.629-636 (Collaboration)
12.	2020/07	Article	Repressor Element 1 Silencing Transcription factor /Neuron-Restrictive Silencing Factor (REST/NRSF) in Social Stress and Depression Prog Neuropsychopharmacol Biol Psychiatry (Collaboration)
13.	2020/06	Article	The impact of oral exposure to low dose tris(2-butoxyethyl)phosphate in allergic asthmatic mice Journal of Applied Toxicology (Collaboration)
14.	2019/02	Article	Relationship between motor function and ultrasonic vocalizations induced by maternal separation in rat pups. The Journal of Veterinary Medical Science 81(2),pp.287-293 (Collaboration)
15.	2019/01	Article	Hatano rats are a suitable metabolic syndrome model for studying feeding behavior, blood pressure levels, and percent body fat The Journal of Veterinary Medical Science 81(1),pp.147-154 (Collaboration)
16.	2018/06	Article	Testing Animal Anxiety in Rats: Effects of Open Arm Ledges and Closed Arm Wall Transparency in Elevated Plus Maze Test JoVE (136) (Collaboration)
17.	2018/05	Article	Early-life exposure to Tris(1,3-dichloroisopropyl) phosphate induces dose-dependent suppression of sexual behavior in male rats J Appl Toxicol. 38(5),pp.649-655 (Collaboration)
18.	2018/05	Article	Male Hatano low-avoidance rats show more active sexual behavior with lower plasma testosterone than high-avoidance rats J Vet Med Sci. 80(7),pp.1179-1182 (Collaboration)
19.	2017/02	Article	Effects of neonatal 17α-ethinyloestradiol exposure on female-paced mating behaviour in the rat. J Appl Toxicol. 37(8),pp.996-1003 (Collaboration)
20.	2016/01	Article	A single neonatal injection of ethinyl estradiol impairs passive avoidance learning and reduces expression of estrogen receptor α in the hippocampus and cortex of adult female rats. PLoS One 11(1.) (Collaboration)
21.	2015/11	Article	Higher detection sensitivity of anxiolytic effects of diazepam by ledge-free open arm with opaque walled closed arm elevated plus maze in male rats. Behav Brain Res 294(Nov 1),pp.131-140 (Collaboration)
22.	2014/01	Article	Dietary deprivation of each essential amino acid induces differential systemic adaptive responses in mice. Molecular Nutrition & Food Research 58(6),pp.1309-1321 (Collaboration)
23.	2012/09	Article	Male Hatano High-avoidance Rats Show High Aversive Learning and High Anxiety-like Behaviors as Compared to Male Low-avoidance Rats Experimental Animals 61(5),pp.517-524 (Collaboration)
24.	2010/10	Article	Maternal exposure to isobutyl-paraben impairs social recognition in adult female rats Experimental Animals 59(5),pp.631-635 (Collaboration)
25.	2009/10	Article	Maternal isobutyl-paraben exposure alters anxiety and passive avoidance test performance in adult male rats Neuroscience Research 65(2),pp.136-140 (Collaboration)
26.	2009/08	Article	Maternal isobutyl-paraben exposure decreases plasma corticosterone level in dam and sensitivity to estrogen in female offspring rats The Journal of Veterinary Medical Science 71(8),pp.1027-1033 (Collaboration)
27.	2009/04	Article	Cardiotonic effect of Apocynum venetum L. extracts on the isolated guinea pig atrium Natural Medicines 63(2),pp.111-116 (Collaboration)
28.	2008/10	Article	Expression of nerve growth factor and its receptors trkA and p75 and inhibin alpha-subunit in the ovarian interstitial cells of lactating golden hamsters The Journal of Reproduction and Development 54(5),pp.397-401 (Collaboration)
29.	2008/06	Article	Developmental exposure to pentachlorophenol affects the expression of thyroid hormone receptor b1 and synapsin I in brain, resulting in thyroid function vulnerability in rats Endocrine 33(3),pp.277-284 (Collaboration)
30.	2007/01	Article	Bisphenol a induces transforming growth factor-beta3 mRNA in the preoptic area: a cDNA expression array and northern blot study Neuroscience Letter 411(1),pp.81-85 (Collaboration)
31.	2006/10	Article	Effects of bilateral efferent duct ligation on sperm motility and secretion of FSH, LH, inhibin and testosterone in adult male rats Endocrine 30(2),pp.151-160 (Collaboration)
32.	2006/10	Article	Effects of p-nonylphenol and 4-tert-octylphenol on the anterior pituitary functions in adult ovariectomized rats Neuroendocrinology 84(1),pp.14-20 (Collaboration)
33.	2005/08	Article	Expression of nerve growth factor (NGF), and its receptors TrkA and p75 in the reproductive organs of the adult male rats Zoological Science 22(8),pp.933-937 (Collaboration)
34.	2005/06	Article	Dorsomedial hypothalamic corticotropin-releasing factor (CRF) mediation of exercise-induced anorexia American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 288(6),pp.R1800-R1805 (Collaboration)
35.	2004/05	Article	Exposure to bisphenol a during gestation and lactation causes loss of sex difference in corticotropin-releasing hormone-immunoreactive neurons in the bed nucleus of the stria terminalis of rats Psychoneuroendocrinology 29(4),pp.475-485 (Collaboration)
36.	2002/06	Article	Butyl benzyl phthalate, an endocrine disrupter, inhibits pulsatile luteinizing hormone secretion under an insulin-induced hypoglycemic state in ovariectomized rats Journal of Neuroendocrinology 14(6),pp.486-491 (Collaboration)
37.	2001/08	Article	The endocrine disruptors butyl benzyl phthalate and bisphenol a increase the expression of progesterone receptor messenger ribonucleic acid in the preoptic area of adult ovariectomized rats Neuroendocrinology 74(2),pp.77-81 (Collaboration)
38.	2001/03	Article	Effects of gestational and lactational exposure to bisphenol a on the hypothalamic control mechanism of reproduction in female rats pp.115-126 (Collaboration)
39.	1998/11	Article	Insulin-induced hypoglycemia does not impaire the surge of luteinizing hormone (LH) secretion in the proestrous rat Neuroscience Letters 256(3),pp.131-134 (Collaboration)
Display 5 items
Display all(39)

■ Conference Presentations

1.	2025/07/11	Effects of neonatal exposure to 3-Methyl-4-Nitrophenol on partner preference in female rats (The 19th International Congress of Comparative Endocrinology)
2.	2025/07/09	Effects of lignin sulfonic acid on anxiety-like behavior, organ weights, and plasma hormone levels in male rats (The 19th International Congress of Comparative Endocrinology)
3.	2024/10/27	Differences in fecal bacterial composition between inbred Hatano strains of rats with high/low emotional reactivity (日本動物心理学会第84回大会)
4.	2024/10/27	Intrahippocampal Neuromedin U (NmU) is involved in learning and memory, not in anxiety like behavior in the male rat. (日本動物心理学会第84回大会)
5.	2024/10/27	Sustained effect of fenders for suppressing regurgitation behavior and changes of fecal cortisol in captive bottlenose dolphins (日本動物心理学会第84回大会)
6.	2023/11/14	Does pituitary adenylate cyclase-activating polypeptide (PACAP) cause anxiolytic properties in the rat hippocampus？ (Neuroscience 2023)
7.	2023/11/14	Exposure to tris (1,3-dichloro-2-propyl) phosphate (TDCIPP) at periods of juvenile and adult suppresses sexual behavior, but not neonatal and adult in male rats (Neuroscience 2023)
8.	2023/10/08	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) antagonist Cause Anxiolytic effects in the Hippocampus of Sprague-Dawley Rat (日本動物心理学会第83回大会)
9.	2022/12/10	Effects of Chronic L-α-glycerylphosphorylcholine (α-GPC) Ingestion on Spatial Memory in Adult Male Rats (The 22nd International Congress of Nutrition)
10.	2022/11/13	Effects of Chronic L-α-glycerylphosphorylcholine (α-GPC) Ingestion on Spatial Memory and the hippocampal formation in Adult Male Rats (Neuroscience2022)
11.	2022/11/12	Administration of progesterone, but not 17-beta-estradiol, tends to improve diazepam-induced place recognition memory deficit in female rats (Neuroscience2022)
12.	2022/11/12	Identifying anxiety-related genes in the hippocampus of Hatano rats. (Neuroscience2022)
13.	2021/03/06	(The 91st Annual Meeting of the Japanese Society for Hygiene)
14.	2021/03/06	(The 91st Annual Meeting of the Japanese Society for Hygiene)
15.	2019/10/19	Genetic and Endocrinological Analysus of Stress Response and Angsiety-Like Behaviour by Cross-Fostered Hatano Rats (Society for Neuroscience 2019.)
16.	2019/10/19	Sutability of sociality research using Hatano rats (Society for Neuroscience 2019.)
17.	2019/10/19	The effect of environmental enrichment on hippocampal neuroplasticity-related genes in Hatano rats. (Society for Neuroscience 2019.)
18.	2019/06/22	Effect of Environmental Enrichment on Reproductive Behavior in Hatano Rats. (The 14th International Conference on Environmental Enrichment (ICEE KYOTO 2019).)
19.	2019/06/22	The Effects of Environmental Enrichment on Anxiety-Like Behavior, Learning Behavior and Hippocampal Gene Expression in Hatano Rats. (The 14th International Conference on Environmental Enrichment (ICEE KYOTO 2019).)
20.	2018/08/01	Assessing the Effect of Environmental Enrichment on Hatano Rat Sexual Behavior and the Investigation of its Contribution Factor by use of Social Interaction Test. (18th Asian Australasian Animal Production Congress)
21.	2018/08/01	The Effect of Environmental Enrichment on Emotional Behavior snd Hippocampus Gene Expression in Hatano Rats . (18th Asian Australasian Animal Production Congress)
22.	2018/07/01	Littermates can affect on maternal-separation inducide ultrasonic vocalization in rat pups. (18th World Congress of Basic and Clinical Pharmacology)
23.	2018/07/01	The effect of environmental enrichment on hippocampus gene expression and blood corticosterone concentration in Hatano rats. (18th World Congress of Basic and Clinical Pharmacology)
24.	2017/11/11	Contextual fear conditioning test in Hatano high and low avoidance rats (Neuroscience 2017)
25.	2017/11/11	Effect of environmental enrichment on emotional, learning behavior, and hippocampus BDNF expression in Hatano rats. (Neuroscience 2017)
26.	2017/11/11	Hatano rats suitable as metabolic syndrome model focusing on feeding behavior and physiological strain differences. (Neuroscience 2017)
27.	2017/11/11	Strain differences of learning ability and emotional behavior in Hatano high and low avoidance rats (Neuroscience 2017)
28.	2017/03/15	Behavioral characteristics of Hatano high and low avoidance rats that have been respectively bred based on the active avoidance learning test
29.	2017/03/15	Effect of environmental enrichment on emotional and reproductive behavior in Hatano rats
30.	2015/07/28	Altered emotional reactivity of offspring induced by cross-fostering between Hatano high and low active avoidance rats, and its relationship with maternal care
31.	2014/12/09	Effect of anti-androgen and tris(1,3- dichloro-2-propyl)phosphate (TDCIPP) on sexual behavior, sexual preference, organ weight and plasma concentration of testosterone of male rats
32.	2014/12/09	Effects of Neonatal Ethynyl Estradiol Exposure to Female Rats on Partner Preference, Territorial and Sexual Behavior
33.	2014/11/15	Cross-fostering between Hatano high and low active avoidance rats altered emotional reactivity of male offspring (Neuroscience 2014)
34.	2014/09/11	Relationship between elevated plus maze arm structure and anxiety-like behavior in rats: the presence or absence of open arm ledges vs opaqueness of closed arm stucture walls
35.	2013/12/12	Exposure to ethinyl estradiol within 24 hours of birth decreases the expression levels of ERα in adult female rats
36.	2013/09/12	Effects of neonatal ethynyl estradiol exposure to female rats on sexua behavior
37.	2013/06/22	EFFECTS OF NEONATAL ETHYNYL ESTRADIOL EXPOSURE TO FEMALE RATS ON FEEDING, LEARNING AND SEXUAL BEHAVIOR
38.	2013/01/05	EFFECTS OF NEONATAL SINGLE INJECTION OF ETHINYL ESTRADIOL ON FEEDING, LEARNING AND SEXUAL BEHAVIORS IN ADULT FEMALE RATS (The 17th FAVA Congress)
39.	2012/12/19	Effect of perinatal ethynyl estradiol exposure on female exploratory behavior (The 15th Annual Meeting of the Japan Society of Endocrine Disrupters Research)
40.	2012/12/19	Estrogen receptor α expression levels vary in adult female rats exposed to Ethynyl estradiol within 24 hours of birth (The 15th Annual Meeting of the Japan Society of Endocrine Disrupters Research)
41.	2012/12/18	Effect of perinatal ethynyl estradiol exposure on female rats' partner preference (The 15th Annual Meeting of the Japan Society of Endocrine Disrupters Research)
42.	2012/09/20	Male Hatano High-avoidance Rats Show High Aversive Learning and High Anxiety-like Behaviors as Compared to Male Low-avoidance Rats (The 35th Annual Meeting of the Japan Neuroscience Society)
43.	2012/09	(The 105th Society for Reproduction and Development Annual Meeting)
44.	2012/08/31	(THe 17th Japanese Society for Behavioral Neuroendocrinology)
45.	2011/06/02	The characteristics of Hatano high- and low-avoidance rats as a model for developmental disorder (8th International Congress of Comparative Physiology and Biochemistry)
46.	2010/03	Behavioral profile in ovariectomized female Hatano high- and low-avoidance rats (The 14th International Congress of Endocrinology)
47.	2009/09	Maternal isobutyl-paraben exposure alters anxiety, learning performance, and social recognition in adult rats (The 36th Japan Neuroendocrine Society)
48.	2006/07	Developmental exposure to Pentachlorophenol affects thyroid hormone responsive gene in the brain but not stress response (The 29th Annual Meeting of the Japan Neuroscience Society)
49.	2003/10	Reductions of food intake arising from voluntary running wheel exercise are attenuated by central injection of a CRF antagonist (Neuroscience 33rd Annual Meeting)
50.	1998/10	Effects of environmental estrogens on pulsatile luteinizing hormone secretion in adult female rats (The 4th International Congress of neuroendocrinology)
Display 5 items
Display all(50)

■ Academic Qualifications

1.	1997/04～2001/03	〔Doctorial Course〕, Graduate School, Division of Medicine, Yokohama City University, Completed, PhD
2.	1991/04～1997/03	Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Graduated,

■ researchmap Researcher Code

5000004204

■ Certificates and Licenses

1997/09

D.V.M.

■ Web Sites

Laboratory of Animal Behavior and Environmental Science in the School of Agriculture at Meiji University

■ Current Specialized Field

Laboratory animal science, Animal production science, Environmental impact assessment (Key Word：behavior, neuroendocrine, environmental factor, developmental disorder, animal welfare)